Trailing by one goal at the end of the third quarter, the Tar Heels (9-4) outscored the Pride (6-6) by 5-1 in the fourth.
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No. 3 Massachusetts 8, Drexel 6: Tim McCormack made 14 saves and the Minutemen improved to 11-0, a first in program history, in Bethpage, N.Y.
Steve D'Amario and Anthony Biscardi each scored twice. UMass tops the Colonial Athletic Association standings with a 4-0 record. The Dragons fell to 5-7, 3-2.
No. 12 Villanova 10, St. John's 8: C.J. Small scored both of his goals during a 4-1 run in the fourth quarter to lead the host Wildcats (8-4, 4-0 Big East) past the Red Storm (6-5, 2-3).
Matt Bell (St. Mary's) led Villanova with four goals.
No. 13 Syracuse 19, Rutgers 6: The Orange (6-5, 3-1 Big East) displayed its high-powered offense by scoring 12 goals straight and beating the Scarlet Knights (5-8, 1-4) at the ESPNU Warrior Classic in Charlotte.
No. 4 Florida 17, No. 18 Vanderbilt 5: Kitty Cullen (McDonogh) scored a game-high five goals and the host Gators (14-2, 4-0 American Lacrosse Conference) won their 10th straight.
No. 2 Syracuse 22, No. 11 Georgetown 11: Kailah Kempney and Devon Collins combined to score 10 goals, five each, to power the host Orange (10-2, 4-0 Big East) past the Hoyas (8-5, 4-2). Syracuse has won nine straight.
No. 6 Dartmouth 9, No. 15 Penn 7: Sarah Plumb scored two of her four goals during a 4-0 run to close out the game as the host Big Green (9-2, 5-0 Ivy League) upset the Quakers (6-5, 4-1).
No. 7 Notre Dame 16, Connecticut 9: Maggie Tamasitis had a league-record eight assists as the Fighting Irish (10-2, 4-2 Big East) beat the host Huskies (7-5, 0-4).
Jaimie Morrison (four goals) led a balanced Notre Dame offense that scored eight goals each half.